IISc scientists uncover key mechanism that allows TB to persist in humans for decades

New Delhi, (PTI) Researchers at the Indian Institute of Science (IISc) have uncovered an important mechanism that allows the tuberculosis (TB) bacterium to persist in the human host for decades.

The team, including researchers from the National Centre for Biological Sciences (NCBS) and Institute For Stem Cell Science and Regenerative Medicine (InStem), Bengaluru, found that a single gene involved in the production of iron-sulphur clusters could be crucial for the persistence of the TB bacterium.

TB is caused by Mycobacterium tuberculosis (Mtb), which can be present in the human body for decades without any symptoms.

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